• Association between soft drink consumption and mortality in 10 European countries 

      Mullee, Amy; Romaguera, Dora; Pearson-Stuttard, Jonathan; Viallon, Vivian; Stepien, Magdalena; Freisling, Heinz; Fagherazzi, Guy; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Kaaks, Rudolf; Boeing, Heiner; Aleksandrova, Krasimira; Tjønneland, Anne; Halkjær, Jytte; Overvad, Kim; Weiderpass, Elisabete; Skeie, Guri; Parr, Christine Louise; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Cirera, Lluis; Ardanaz, Eva; Khaw, Kay-Tee; Tong, Tammy Y.N.; Schmidt, Julie A.; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, Hendrik Bastiaan; Verschuren, W.M. Monique; Boer, Jolanda M.A.; Vermeulen, Roel; Ramne, Stina; Sonestedt, Emily; Van Guelpen, Bethany; Holgersson, Pernilla Lif; Tsilidis, Konstantinos K.; Heath, Alicia K.; Muller, David; Riboli, Elio; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-03)
      <i>Importance</i> - Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date.<p><p> <i>Objective</i> - To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality.<p><p> <i>Design, ...
    • Associations between dietary inflammatory scores and biomarkers of inflammation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Lécuyer, Lucie; Laouali, Nasser; Viallon, Vivian; Artaud, Fanny; Hébert, James R.; Shivappa, Nitin; Agudo, Antonio; Tjønneland, Anne; Mellemkjær, Lene; Kaaks, Rudolf; Katzke, Verena A.; Schulze, Matthias B.; Frenoy, Pauline; Mancini, Francesca Romana; De Magistris, Maria Santucci; Macciotta, Alessandra; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Jensen, Torill; Olsen, Karina Standahl; Skeie, Guri; Chirlaque, María-Dolores; Petrova, Dafina; Castro-Espin, Carlota; Quirós, J. Ramón; Guevara, Marcela; Amiano, Pilar; Borné, Yan; Sandström, Maria; Nilsson, Lena Maria; Heath, Alicia K.; Mayen, Ana-Lucia; Huybrechts, Inge; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Dossus, Laure; Rinaldi, Sabina; Truong, Thérèse (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-17)
      Background - Since the first version of the dietary inflammatory index (DII®) developed in the past decade, several other versions have been developed. However, to date no study has attempted to compare these versions with respect to their associations with biomarkers of inflammation.<p> <p>Objective - We aimed to investigate the relationship between four dietary inflammatory scores [DII, two ...
    • Coffee, tea and melanoma risk: findings from the European Prospective Investigation into Cancer and Nutrition 

      Caini, Saverio; Masala, Giovanna; Saieva, Calogero; Kvaskoff, Marina; Savoye, Isabelle; Sacerdote, Carlotta; Hemmingsson, Oskar; Hammer Bech, Bodil; Overvad, Kim; Tjønneland, Anne; Petersen, Kristina E.N.; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Cervenka, Iris; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Floegel, Anna; Trichopoulou, Antonia; Valanou, Elisavet; Kritikou, Maria; Tagliabue, Giovanna; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Veierød, Marit Bragelien; Ghiasvand, Reza; Lukic, Marko; Quirós, José Ramón; Chirlaque, Maria-Dolores; Ardanaz, Eva; Salamanca Fernández, Elena; Larrañaga, Nerea; Zamora-Ros, Raul; Maria Nilsson, Lena; Ljuslinder, Ingrid; Jirström, Karin; Sonestedt, Emily; Key, Timothy J.; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc; Huybrechts, Inge; Murphy, Neil; Tsilidis, Konstantinos K.; Weiderpass, Elisabete; Palli, Domenico (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-20)
      In vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma; however, epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC ...
    • Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study 

      Cordova, Reynalda; Kliemann, Nathalie; Huybrechts, Inge; Rauber, Fernanda; Vamos, Eszter P.; Levy, Renata Bertazzi; Wagner, Karl-Heinz; Viallon, Vivian; Casagrande, Corinne; Nicolas, Geneviève; Dahm, Christina Catherine; Zhang, Jie; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Chiristine; Mancini, Francesca Romana; Laouali, Nasser; Katzke, Verena; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; van der Schouw, Yvonne T; Derksen, Jeroen W.G.; Rylander, Charlotta; Skeie, Guri; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Brunkwall, Louise; Ramne, Stina; Bodén, Stina; Perez-Cornago, Aurora; Heath, Alicia K; Vineis, Paolo; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher J.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background - There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.<p> <p>Methods - This prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from 9 European ...
    • Development and validation of circulating CA125 prediction models in postmenopausal women 

      Sasamoto, Naoko; Babic, Ana; Rosner, Bernard A.; Fortner, Renée T.; Vitonis, Allison F; Yamamoto, Hidemi; Fichorova, Raina N.; Titus, Linda J.; Tjønneland, Anne; Hansen, Louise; Kvaskoff, Marina; Fournier, Agnès; Mancini, Francesca Romana; Boeing, Heiner; Trichopoulou, Antonia; Peppa, Eleni; Karakatsani, Anna; Palli, Domenico; Grioni, Sara; Mattiello, Amalia; Tumino, Rosario; Fiano, Valentina; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Gram, Inger Torhild; Quirós, José Ramón; Lujan-Barroso, Leila; Sánchez, María-José; Colorado-Yohar, Sandra; Barricarte, Aurelio; Amiano, Pilar; Idahl, Annika; Lundin, Eva; Sartor, Hanna; Khaw, Kay-Tee; Key, Timothy J.; Muller, David; Riboli, Elio; Gunter, Marc; Dossus, Laure; Trabert, Britton; Wentzensen, Nicolas; Kaaks, Rudolf; Cramer, Daniel W.; Tworoger, Shelley S.; Terry, Kathryn L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-26)
      <i>Background</i> - Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to improve its performance as screening biomarker.<p><p> <i>Methods</i> - We developed and validated ...
    • Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition 

      Park, Jin Young; Bueno-de-Mesquita, Hendrik Bastiaan; Ferrari, Pietro; Weiderpass, Elisabete; de Batlle, Jordi; Tjønneland, Anne; Kyrø, Cecilie; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kritikou, Maria; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.; Skeie, Guri; Merino, Susana; Duell, Eric J.; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Ardanaz, Eva; Gylling, Björn; Schneede, Jørn; Ericson, Ulrika; Sternby, Hanna; Khaw, Kay-Tee; Bradbury, Kathryn E.; Huybrechts, Inge; Aune, Dagfinn; Vineis, Paolo; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-04)
      Pancreatic cancer (PC) has an exceptionally low survival rate and primary prevention strategies are limited. Folate plays an important role in one‐carbon metabolism and has been associated with the risk of several cancers, but not consistently with PC risk. We aimed to investigate the association between dietary folate intake and PC risk, using the standardised folate database across 10 European ...
    • Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort 

      Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Goñi, Fernando; Cirera, Lluís; Donat-Vargas, Carolina; Alguacil, Juan; Iglesias, Mar; Tjønneland, Anne; Overvad, Kim; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Johnson, Theron; Kühn, Tilman; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Verschuren, Monique; Vermeulen, Roel; Rylander, Charlotta; Nøst, Therese Haugdahl; Rodriguez-Barranco, Miguel; Molinuevo, Amaia; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sund, Malin; Key, Tim; Ye, Weimin; Jenab, Mazda; Michaud, Dominique; Matullo, Giuseppe; Canzian, Federico; Kaaks, Rudolf; Nieters, Alexandra; Nöthlings, Ute; Jeurnink, Suzanne; Chajes, Veronique; Matejcic, Marco; Gunter, Marc; Aune, Dagfinn; Riboli, Elio; Agudo, Antoni; Gonzalez, Carlos Alberto; Weiderpass, Elisabete; Bueno-de-Mesquita, Hendrik Bastiaan; Duell, Eric J.; Vineis, Paolo; Porta, Miquel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-23)
      <i>Background</i> - The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex diseases.<p> <p><i>Objectives</i> - First, to summarize the main design features of a prospective case-control study –nested within the European Prospective Investigation ...
    • Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study 

      Freisling, Heinz; Noh, Hwayoung; Slimani, Nadia; Chajès, Véronique; May, Anne M.; Peeters, Petra H; Weiderpass, Elisabete; Cross, Amanda J.; Skeie, Guri; Jenab, Mazda; Mancini, Francesca Romana; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Katzke, Verena A.; Kühn, Tilman; Steffen, Annika; Boeing, Heiner; Tjønneland, Anne; Kyrø, Cecilie; Hansen, Camilla P.; Overvad, Kim; Duell, Eric J.; Redondo-Sánchez, Daniel; Amiano, Pilar; Navarro, Carmen; Barricarte, Aurelio; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Aune, Dagfinn; Ward, Heather; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Berrino, Franco; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Bueno-De-Mesquita, Hendrik Bastiaan; Ericson, Ulrika; Sonestedt, Emily; Winkvist, Anna; Braaten, Tonje; Romieu, Isabelle; Sabaté, Joan (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-07-21)
      <p><i>Purpose</i>: There is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.</p> <p><i>Methods</i>: This study includes 373,293 men and women, 25–70 years old, recruited between 1992 and 2000 from 10 European countries in the European ...
    • Nutrient-wide association study of 92 foods and nutrients and breast cancer risk 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Papadimitriou, Nikos; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Fagherazzi, Guy; Boeing, Heiner; Ferrari, Pietro; Olsen, Anja; Tjønneland, Anne; Arveux, Patrick; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Kuhn, Tilman; Turzanski-Fortner, Renee; Schulze, Matthias B.; Karakatsani, Anna; Thriskos, Paschalis; Thrichopoulou, Antonia; Masala, Giovanna; Contiero, Paolo; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Bas; Bakker, Marije F.; van Gils, Carla H.; Olsen, Karina Standahl; Skeie, Guri; Lasheras, Cristina; Agudo, Antonio; Rodrigues-Barranco, Miguel; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Drake, Isabel; Ericson, Ulrika; Johansson, Ingegerd; Winkvist, Anna; Key, Tim; Freisling, Heinz; His, Mathilde; Huybrechts, Inge; Christakoudi, Sofia; Ellingjord-Dale, Merete; Riboli, Elio; Tsilidis, Konstantinos K.; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)
      <i>Background</i> - Several dietary factors have been reported to be associated with risk of breast cancer, but to date, unequivocal evidence only exists for alcohol consumption. We sought to systematically assess the association between intake of 92 foods and nutrients and breast cancer risk using a nutrient-wide association study.<p> <p><i>Methods</i> - Using data from 272,098 women ...
    • Pre-diagnostic copper and zinc biomarkers and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort 

      Stepien, Magdalena; Jenab, Mazda; Freisling, Heinz; Becker, Niels-Peter; Czuban, Magdalena; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Savoye, Isabelle; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Weiderpass, Elisabete; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Boden, Stina; van Guelpen, Behany; Wareham, Nick; Khaw, Kay-Tee; Bradbury, Kathryn E.; Cross, Amanda J.; Schomburg, Lutz; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed; Preprint; Manuskript, 2017-07-01)
      Adequate intake of copper and zinc, two essential micronutrients, are important for antioxidant functions. Their imbalance may have implications for development of diseases like colorectal cancer (CRC), where oxidative stress is thought to be etiologically involved. As evidence from prospective epidemiologic studies is lacking, we conducted a case-control study nested within the European Prospective ...
    • Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma 

      Stepien, Magdalena; Lopez-Nogueroles, Marina; Lahoz, Agustın; Kühn, Tilman; Perlemuter, Gabriel; Voican, Cosmin; Ciocan, Dragos; Boutron-Ruault, Marie-Christine; Jansen, Eugéne H.J.M.; Viallon, Vivian; Leitzmann, Michael; Tjønneland, Anne; Severi, Gianluca; Mancini, Francesca Romana; Dong, Catherine; Kaaks, Rudolf; Fortner, Renée T.; Bergmann, Manuela M.; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Skeie, Guri; Merino, Susana; Zamora-Ros, Raúl; Sánchez, Maria Jose; Amiano, Pilar; Huerta, José María; Barricarte, Aurelio; Sjöberg, Klas; Ohlsson, Bodil; Nyström, Hanna; Werner, Mårten; Perez-Cornago, Aurora; Schmidt, Julie A.; Freisling, Heinz; Scalbert, Augustin; Weiderpass, Elisabete; Christakoudi, Sofia; Gunter, Marc; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-29)
      Bile acids (BAs) play different roles in cancer development. Some are carcinogenic and BA signaling is also involved in various metabolic, inflammatory and immune-related processes. The liver is the primary site of BA synthesis. Liver dysfunction and microbiome compositional changes, such as during hepatocellular carcinoma (HCC) development, may modulate BA metabolism increasing concentration of ...